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Leandro Augusto Barbosa Selected Research

Neoplasms (Cancer)

12/2021Implications of Synthetic Modifications of the Cardiotonic Steroid Lactone Ring on Cytotoxicity.
12/2019New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.
11/2018Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
10/2014Effects of digoxin and Na, K-ATPase immunoexpression on human oral squamous carcinomas.
1/2014Ouabain-induced alterations of the apical junctional complex involve α1 and β1 Na,K-ATPase downregulation and ERK1/2 activation independent of caveolae in colorectal cancer cells.
9/2009[Bioethics and nutrition in adult patients with cancer in palliative care].

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Leandro Augusto Barbosa Research Topics

Disease

6Neoplasms (Cancer)
12/2021 - 09/2009
2Seizures (Absence Seizure)
07/2023 - 01/2018
2Neuroinflammatory Diseases
03/2023 - 01/2019
2Carcinoma (Carcinomatosis)
12/2021 - 11/2018
1Epilepsy (Aura)
07/2023
1Nervous System Diseases (Neurological Disorders)
07/2023
1COVID-19
01/2023
1Mycoses (Diseases, Fungus)
07/2022
1Brain Diseases (Brain Disorder)
01/2021
1Ovarian Neoplasms (Ovarian Cancer)
12/2019
1Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2019
1Heart Failure
11/2018
1Prostatic Neoplasms (Prostate Cancer)
11/2018
1Iron Overload
03/2018
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
10/2014
1Squamous Cell Carcinoma of Head and Neck
10/2014
1Colorectal Neoplasms (Colorectal Cancer)
01/2014

Drug/Important Bio-Agent (IBA)

10Adenosine Triphosphatases (ATPase)IBA
07/2023 - 01/2014
3Ouabain (G Strophanthin)IBA
03/2023 - 01/2014
3Digoxin (Digitek)FDA LinkGeneric
12/2021 - 10/2014
2LipopolysaccharidesIBA
03/2023 - 01/2019
2DigitoxigeninIBA
12/2021 - 11/2018
2Cardiac GlycosidesIBA
01/2021 - 11/2018
2Proteins (Proteins, Gene)FDA Link
10/2014 - 01/2014
1AntioxidantsIBA
07/2023
1Kainic Acid (Kainate)IBA
07/2023
1Pilocarpine (Ocusert)FDA LinkGeneric
07/2023
1Pentylenetetrazole (Metrazol)IBA
07/2023
1Neuroprotective AgentsIBA
07/2023
1Glutamic Acid (Glutamate)FDA Link
03/2023
14-aminoquinolineIBA
01/2023
1chloroquine diphosphateFDA LinkGeneric
01/2023
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2023
1Antifungal AgentsIBA
07/2022
1Fluconazole (Zonal)FDA LinkGeneric
07/2022
1LactonesIBA
12/2021
1Benzylidene CompoundsIBA
01/2021
1BufanolidesIBA
12/2019
1bufadienolideIBA
12/2019
1CaspasesIBA
12/2019
1LipidsIBA
01/2019
1Paclitaxel (Taxol)FDA LinkGeneric
01/2019
1Hormones (Hormone)IBA
11/2018
1SurvivinIBA
11/2018
1Docetaxel (Taxotere)FDA Link
11/2018
1AndrogensIBA
11/2018
1CardenolidesIBA
11/2018
13- (2- (1- amantadine)- 1- one- ethylamine)digitoxigeninIBA
11/2018
1Cyclin B1IBA
11/2018
1EnzymesIBA
03/2018
1Membrane LipidsIBA
01/2018

Therapy/Procedure

2Therapeutics
07/2023 - 11/2018
1Palliative Care (Palliative Therapy)
09/2009